sleep disorder
Conditions
Interventions
Experimental group:Bifidobacterium triple live enteric-coated capsules, 0.21g each morning and evening, a month is a course of treatment
Control group:Routine treatment
Sponsors
Huai'an Hospital Affiliated to Xuzhou Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) patients with chronic renal failure who had received stable hemodialysis for more than 3 months before being enrolled; 2) aged more than 18 years male and female Chinese citizens; 3) no antibiotics were used in the four weeks before the start of the experiment; no probiotics were used within three weeks; 4) no special diet or regular use of bev????????????,0.21g ?????,1?????erages and preparations containing probiotics; 5) conforms to the diagnostic criteria of insomnia in the third edition of international classification of sleep disorders, and insomnia occurs after dialysis treatment; 6) Pittsburgh's sleep quality score is equal or more than to 7 points; 7) informed consent of the patient and signed informed consent.
Exclusion criteria
Exclusion criteria: 1) Pittsburgh's sleep quality score is less than 7 points; 2) end-stage heart failure (NYHAI IV); 3) a serious history of liver disease; 4) ALT or AST is 2 times higher than the upper limit of the normal value; 5) suffering from malignant tumor; the tumor was not controlled, in the active period, the expected survival time was less than 1 years; 6) was treated with immunosuppressive agents or other biological agents within 3 months; 7) taking part in the test within 3 months; 8) a person with a history of mental illness; 9) life expectancy is less than 12 months; 10) take other drugs to improve sleep and other sleep therapists; 12) there are serious physical symptoms, such as bone pain and itchy skin; 13) severe anemia (hemoglobin < 60 micrograms / L) or fatigue caused by malnutrition (serum albumin < 30 microgram / liter).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Melatonin; | — |
Countries
China
Contacts
Public ContactDonghui Zheng
Huai'an Hospital Affiliated to Xuzhou Medical University
Outcome results
None listed