early digestive tract tumor
Conditions
Interventions
epinephrine group:Using epinephrine in submucosal injection
Hemocoagulase group:Using hemocoagulase in submucosal injection
Sponsors
Changhai hospital, Second Military Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 75 years old,males or females; 2. Patients with superficial tumor of the esophagus, stomach or colon underwent ESD; 3. Cardiopulmonary function is suitable for ESD and no coagulation system diseases; 4. Hb, PLT, PT, INR and APTT reached ESD indication; 5. Freely given informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with mental and neurological diseases, serious cardiopulmonary diseases, liver and kidney diseases, immune and hematological diseases, or other serious diseases that affect their survival (such as cancer, AIDS, etc.); 2. Coagulation disorders (including thrombocytopenia, hemophilia, von Willebrand disease), or those who use anticoagulants or antiplatelet drugs could not be discontinued; 3. Risk factors for thrombosis (such as long-term bed-ridden, history of venous thrombosis, etc.); 4. Patients allergic to the product or a product of the same kind; 5. Planning pregnancy, pregnant and breastfeeding women; 6. Patients joined in other clinical trials 3 months before ESD or during the trial period; 7. Other reasons inappropriately to participate in the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemostasis effect in ESD; | — |
Secondary
| Measure | Time frame |
|---|---|
| bleeding after ESD; | — |
Countries
China
Contacts
Public ContactLiu Feng
Changhai hospital, Second Military Medical University
Outcome results
None listed