Early lung cancer
Conditions
Interventions
Gold Standard:Pathological diagnosis
the 
amount 
of 
in 
peripheral 
Sponsors
The Second Affiliated Hospital of Soochow University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Aged18 years male or female; 2) No acute severe disease; 3) Pulmonary nodules found on chest radiographs or LDCT examinations and disseminated pulmonary tuberculosis (diameter: 5mm=nodules=3cm). There are microscopic examinations, biopsy or indications for surgery (need to follow-up Pathological diagnosis results); 4) Patients with previously diagnosed lung nodules have not been diagnosed; 5) No history of surgical treatment of the lungs; 6) Patients who have not received targeted drugs, biological treatments, immunosuppressants, and modulators; 7) No organ transplant; 8) Written written informed consent and compliance with study protocol before willingness to conduct clinical research
Exclusion criteria
Exclusion criteria: 1) Pulmonary nodules have undergone surgical treatment; (considering that surgery has been performed, there is interference with the study); 2) history of organ transplantation such as lung transplantation; (consider the use of allogeneic genes and immunosuppressive agents); 3) Pregnancy or lactation; (Considering the inability to perform regular CT follow-up and the effects of fetal components); 4) HIV-positive or AIDS-related disease is known only; (taking into account interference with the use of immune drugs); 5) are receiving targeted drugs, immunosuppressive agents, immunomodulators, biological therapy patients; 6) Pulmonary tuberculosis during active period (consider infectious and referral loss factors); 7) RNA-like viral infections such as SARS, HIV, hepatitis virus (except for hepatitis B, other four Species are RNA viruses), influenza virus, bird flu virus, H5N1, Ebola, hemp Rash; 8) Various hematological diseases such as leukemia, lymphoma, aplastic anemia, MDS, Other types of anemia, hemolysis, hemophilia, DIC, etc.; 9) The history of blood transfusion (within 3 to 6 years) and the potential for blood transfusion; 10) Patients with neurological and mental diseases that cannot be matched; 11) Emergency treatment for acute and severe diseases; 12) Written written informed consent and compliance with study protocol before reluctant to conduct clinical studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pathology;The amount of deliberate exosomes in the peripheral blood;The amount of specific exosomes in cancerous tissue;The amount of specific exosomes in adjacent tissues; | — |
Countries
China
Contacts
Public ContactGong Jianping
The Second Affiliated Hospital of Soochow University
Outcome results
None listed