hemolysis
Conditions
Interventions
(2)Hb
(3)RBC count
(4)Ret%
(8)plasma free Hb
(11)urinary RBC
(12)urine hemo flavin
(13) etiology
Sponsors
Institute of Hematology & Blood Disease Hospital, Chinese Academy of Medical Science
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Clinically confirmed hemolytic anemia patients without clinical intervention and blood transfusion support are included in the hemolytic group, while non hemolytic people(healthy volunteers) are included in the control group. Both outpatient and hospitalized are accepeted; (2) Aged 18 years old; (3) Be able to complete the follow-up observation; (4) Promise not to smoke and keep away from the secondhand smoke environment during the whole test period; (5) Sign the informed consent.
Exclusion criteria
Exclusion criteria: (1) Volunteer's erythrocyte lifespan is in an unsteady state; (2) Hemolytic anemia patients with blood transfusion or have other treatment indications; (3) Patients with severe and uncontrollable infections; (4) Patients with severe heart disease, kidney disease, liver disease and severe cardiopulmonary insufficiency; (6) Patients suffering from?other tumors; (7) Blood transfusion was accepted 1 weeks before this clinical trial; (8) Involving in other clinical trials including drugs and medical devices, in nearly 3 months before this clinical trial; (9) The researchers think it is not appropriate for him or her to take part in this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Erythrocyte lifespan;Abundances of 15N;Erythrocyte lifespan; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemoglobin concentration; | — |
Countries
China
Contacts
Public ContactFengkui Zhang
Anemia Therapeutic Centre, Institute of Hematology & Blood Disease Hospital, Chinese Academy of Medical Science
Outcome results
None listed