early stage breast cancer after breast conservative surgery
Conditions
Interventions
case series:hypofractionated simultaneous integrated boost intensity-modulated radiotherapy (IMRT)
Sponsors
Sichuan Cancer Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Women with 18-70 years of age; 2. Tis, T1-2N0M0 early breast cancer patients after breast conserving surgery according to the 2002 Union for International Cancer Control (UICC) staging standard; 3. pathology confirmed as invasive ductal carcinoma or ductal carcinoma in situ; 4. margin negative; 5. tumor beds marked with metal clip or clear postoperative serum swelling; 6. physical state (Eastern cooperativeOncology Group, ECOG) score 0-1.
Exclusion criteria
Exclusion criteria: 1. neoadjuvant chemotherapy before surgery; 2. margin positive; 3. bilateral breast cancer; 4. no radiotherapy in four months after surgery if the patient does not need adjuvant chemotherapy,or no radiotherapy in six months after surgery if the patient need adjuvant chemotherapy; 5. regional lymph nodes need irradiation; 6. multifocal lesions; 7. distant metastasis; 8. serious cardiopulmonary diseases, mental illness and body dysfunction; 9. history of tumor and (or) history of chest radiation; 10. male breast cancer; 11. contralateral breast cancer; 12. CT simulation can not clearly display the tumor cavity or the metal clips; 13. tumor bed volume / the whole breast volume >30%.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Breast cancer recurrence;local control rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| overall survival rate; | — |
Countries
China
Contacts
Public ContactWang Jie
Sichuan Cancer Hospital
Outcome results
None listed