hemiplegia after cerebral infarction
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. patients with ischemic stroke; 2. single subcortical lesion restricted to the motor pathway involving the internal capsule (IC), basal ganglia (BG), corona radiate (CR),and its neighboring regions in the unilateral hemisphere; 3. right-handed before stroke; 4. aged range from 40 to 75 years old; 5. within 6 weeks after the onset of stroke; 6. being unconscious retardation and stable condition; 7. no psychiatric medications have been taken in one month; 8. Informed consent is signed by the patient or his/her immediate family.
Exclusion criteria
Exclusion criteria: 1. being pregnant or lactation; 2. a history of neurologic or psychiatric disorders;any other health problems or poor physical conditions that may influence participation; 3. any other brain structure damage or abnormalites identified by MRI examinations; 4. any history of alcohol or drug dependency; 5. any MRI contraindications.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Voxel-mirrored homotopic connectivity (VMHC); | — |
Secondary
| Measure | Time frame |
|---|---|
| Fugl-Meyer Assessment;NIH Stroke Scale;Fractional anisotropy (FA);Gray Matter Volume (GMV); | — |
Countries
China
Contacts
Dongzhimen Hospital, Beijing University of Chinese Medicine