Biliary strictures
Conditions
Interventions
Anti-reflux plastic biliary stent group (ARPS):Patients of this group will be inserted with an anti-reflux plastic biliary stent (Micro-Tech (Nanjing) Co. Ltd., Nanjing, China)
Traditional plastic biliary stent group (TPS):Patients of this group will be inserted with a traditional plastic biliary stent (Cook Ireland Ltd, Limerick, Ireland).
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: (1) biliary stricture; (2) the manifestation of biliary obstruction; (3) more than 18 years old; (4) no surgical contraindications.
Exclusion criteria
Exclusion criteria: (1) pregnancy; (2) ever biliary stents insertion or sphicterectomy; (3) with severe respiratory and circulatory system disease; (4) coagulation disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The rate of the occurrence of ascending cholangitis in 12 months;The time of stent patency; | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement of liver function;Electron microscopic examination of the thickness and composition of the attachments in the stent;16S rDNA sequencing of inner wall attachments of stents and tissue microorganism near the papilla;The rate of complications; | — |
Countries
China
Contacts
Public ContactBing Hu/Chuncheng Wu
West China Hospital, Sichuan University
Outcome results
None listed