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Non-invasive ventilation combined with subglottic suction by laryngoscope for the management of acute hypercapnic respiratory failure due to acutely exacerbated COPD

Non-invasive ventilation combined with subglottic suction by laryngoscope for the management of acute hypercapnic respiratory failure due to acutely exacerbated COPD

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800016251
Enrollment
Unknown
Registered
2018-05-22
Start date
2012-11-01
Completion date
Unknown
Last updated
2018-05-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic obstructive pulmonary disease

Interventions

study group:subglottic suction by laryngoscope plus BiPAP
control group:BiPAP

Sponsors

The Fourth People's Hospital of Zhenjiang
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients with AHRF secondary to AE-COPD, aged 50 to 70 years old, hospitalized in Intensive Care Unit (ICU) of The Fourth People’s Hospital of Zhenjiang

Exclusion criteria

Exclusion criteria: 1) patients could not tolerate NIV with BiPAP; 2) clinical state got severer after NIV; 3) the level of consciousness got worse because of hypercapnia or severe hypoxia.

Design outcomes

Primary

MeasureTime frame
the need for endotracheal intubation;—

Secondary

MeasureTime frame
pH value;partial pressure of arterial oxygen (PaO2);partial pressure of arterial carbon dioxide (PaCO2);length of hospital stay;—

Countries

China

Contacts

Public ContactYi ZHU

The Fourth People's Hospital of Zhenjiang

937278542@qq.com+86 18912824389

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026