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A prospective study on predicting the response to treatment with concurrent chemoradiotherapy in patients with esophageal cancer based on tissue and plasma molecular markers

A prospective study on predicting the response to treatment with concurrent chemoradiotherapy in patients with esophageal cancer based on tissue and plasma molecular markers

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800016249
Enrollment
Unknown
Registered
2018-05-22
Start date
2017-05-01
Completion date
Unknown
Last updated
2018-05-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

esophageal cancer

Interventions

A:Platinum-based chemotherapy combined with concurrent radiotherapy
B:Taxane-based chemotherapy combined with concurrent radiotherapy
C:Fluoropyrimidine-based chemotherapy combined with concurrent radiotherapy
D:Multiple chemotherapeutic drugs combined with concurrent radiotherapy

Sponsors

Shantou University Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Be willing and able to provide written informed consent/assent for the trial; 2. Patients with previously untreated/ histologically proven squamous cell carcinoma of the esophagus; 3. Aged 18-75 years male and female; 4. Karnofsky Performance Status (KPS) score = 70; 5. Life expectancy = 3 months.

Exclusion criteria

Exclusion criteria: 1. With other malignant tumors; 2. Associated with other serious underlying diseases.

Design outcomes

Secondary

MeasureTime frame
Distant failure-free survival, D-FFS;Locoregional failure-free survival, LR-FFS;

Primary

MeasureTime frame
Complete response rate;Overall Survival(OS);Tissue proteomics;Plasma cytokine chip;

Countries

China

Contacts

Public ContactLi-Yan Xu

Shantou University Medical School

lyxu@stu.edu.cn+86 754-88900460

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026