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A single center, blank control and exploratory clinical study of propranolol hydrochloride in the treatment of central nervous system hemangioblastoma

A single center, blank control and exploratory clinical study of propranolol hydrochloride in the treatment of central nervous system hemangioblastoma

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800016242
Enrollment
Unknown
Registered
2018-05-21
Start date
2018-06-01
Completion date
Unknown
Last updated
2018-05-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemangioblastoma of the central nervous system

Interventions

Control group:Blank

Sponsors

Department of Neurosurgery of Huashan Hospital Affiliated to Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. MRI diagnosis has one or more HBs of the head or spinal cord, signed informed consent, voluntary participation in the study; 2. the diameter of the tumor located in the skull is less than 3cm, and the diameter of the tumor located in the spinal cord is less than 2cm 3. KPS score >60 score; 4. Aged 18 to 70 years old.

Exclusion criteria

Exclusion criteria: 1. selected as drug users who used VEGF inhibitors before; 2. pairs of hypersensitive patients with sodium hydrochloric acid; 3. patients with allergic asthma and allergic rhinitis; 4. sinus bradycardia, severe atrioventricular block, cardiogenic shock, hypotension; 5. the diameter of tumor is greater than or equal to 4cm, which has the risk of brain hernia; 6. for other clinical trials in the last 3 months; 7. the researchers considered it inappropriate to participate in this clinical trial; 8. pregnant women, lactating women or recent fertility planners.

Design outcomes

Primary

MeasureTime frame
Tumor diameter;

Countries

China

Contacts

Public ContactLiangfu Zhou

Huashan Hospital Affiliated to Fudan University

lfzhouc@126.com+86 13917129991

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026