Middle-aged person with lumbar disc herniation
Conditions
Interventions
PRP group:Application of gelatin sponge impregnated with a mixture of 3 drugs to intraoperative nerve root block
Control group:Gelatin sponge impregnated with saline and no drainage tube placed after surgery
Sponsors
Hong-hui Hospital, Xi'an Jiaotong University College of Medicine
Eligibility
Sex/Gender
All
Age
45 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. imaging examination prompted lumbar disc herniation; 2. Patients had typical symptoms of nerve roots, conservative treatment was ineffective and therefore had surgical indications; 3. middle-aged patients (age 45-60 years old); 4. posterolateral lumbar disc herniation, central lumbar disc herniation without calcification, suitable for MIS-TLIF surgery; 5. a single segmental herniated disc and is a limb of the root; 6. Postoperative CT examination excluded screw-related neurological complications; 7. Failure to incorporate other diseases that may cause lower extremity pain.
Exclusion criteria
Exclusion criteria: 1. combined with intervertebral space infection or postoperative wound infection 2. unstable segment of intervertebral disc, huge herniated intervertebral disc, difficult to open the window, central stenosis, extreme lateral disc herniation; 3. The patient's pain threshold is too low or psychological instability can not be assessed; 4. history of previous spinal surgery, secondary surgery may be associated with nerve root adhesions; 5. The skin test before surgery is allergic to the drug mixture; 6. Patients who use pain pump or intramuscular injection after surgery; 7. pregnant patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS scores of lower limb pain before and 1-10 days after surgery;Length of bed after surgery;Length of hospital stay; | — |
Secondary
| Measure | Time frame |
|---|---|
| Preoperative and postoperative 1-10 days low back pain VAS score;Preoperative and postoperative 3, 6-day JOA score;The incidence of thrombotic complications;The incidence of postoperative nerve root edema reactive pain ;Postoperative satisfaction survey results; | — |
Countries
China
Contacts
Public ContactDing-Jun Hao
Hong-hui Hospital, Xi'an Jiaotong University College of Medicine
Outcome results
None listed