FindTrial
Sign In

Optimal Sequence of Multimodality Treatment in Locally Advanced Cervical Carcinoma

A Randomized Control Trial Comparing Para-aortic Lymphadenectomy plus Chemoradiation Therapy with Upfront Radical Hysterectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800016214
Enrollment
Unknown
Registered
2018-05-19
Start date
2019-01-01
Completion date
Unknown
Last updated
2018-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cervical cancer

Interventions

1:PALD+CCRT
2:LRH

Sponsors

Peking Union Medical College Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Age between 18-75 years; 2. Histologically confirmed squamous cell cancer of the cervix; 3. Estimated life expectancy >= 4 weeks; 4. FIGO stage IB2, IIA2; 5. Chest and abdominal CT scan or PET-CT with no evidence of distant metastasis; 6. Performance status ECOG 3.0×10^9/L, platelets > 100×10^9/L, CCR>60ml/min, serum bilirubin < 1.25×upper normal range).

Exclusion criteria

Exclusion criteria: 1. Evidence of distant metastases; 2. Pregnancy or breast-feeding; 3. Other malignancy in the last 5 years; 4. Previous pelvic or abdominal radiotherapy; 5. Unable to follow-up; 6. Otherwise unfit for surgery.

Design outcomes

Primary

MeasureTime frame
Progression free survival;—

Countries

China

Contacts

Public ContactJiaxin Yang

Peking Union Medical College Hospital

yangjiaxin007@hotmail.com+86 13661160998

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026