hematologic malignacy
Conditions
Interventions
1:fecal microbiota transplantation
2:Oral Probiotics
Sponsors
the First Affiliated Hospital of Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. The informed consent is signed by the subjects or their legal representatives before the start of clinical research; 2. Male and female patients before allogeneic hematopoietic stem cell transplantation low microbial diversity, aged 18-65 years old; 3. Patients after allogeneic hematopoietic stem cell transplantation; 4. ECOG physical status score 0~2 score; 5. No major organ dysfunction.
Exclusion criteria
Exclusion criteria: 1. Patients with severe liver and renal function and heart and lung dysfunction; 2. An uncontrolled or severe infection; 3. It is possible to prevent mental illness from completing the treatment or informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| overall survival;disease-free survival;the incidence of acute GVHD; | — |
Secondary
| Measure | Time frame |
|---|---|
| safety;recurrence rate;the incidence of cGVHD; | — |
Countries
China
Contacts
Public ContactHuang He
the First Affiliated Hospital of Zhejiang University School of Medicine
Outcome results
None listed