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A randomized controlled trial for ephedrine preconditioning in preventing hypotension after general anesthesia induction in elderly patients with hypertension

A randomized controlled trial for ephedrine preconditioning in preventing hypotension after general anesthesia induction in elderly patients with hypertension

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800016202
Enrollment
Unknown
Registered
2018-05-18
Start date
2018-06-01
Completion date
Unknown
Last updated
2018-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypotension prevention after general anesthesia induction

Interventions

experimental group: ephedrine preconditioning

Sponsors

Yongchuan Hospital, Chongqing Medical University, Chongqing, China
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 90 Years

Inclusion criteria

Inclusion criteria: American Society Of Anesthesiologists (ASA) grade II-III; aged 65-90 years; body mass index (BMI) 18-28kg/m2; Patients diagnosed as hypertension (Class I, II, III)

Exclusion criteria

Exclusion criteria: The preoperative blood pressure was more than 180/110mmHg, Liver and kidney dysfunction; arrhythmia, heart failure (NYHAIII/IV); Pericarditis, endocarditis and myocarditis, acute respiratory tract infection; radial artery and internal jugular vein catheterization contraindication; drug allergy; intraoperative and postoperative death or give up the treatment of patients

Design outcomes

Primary

MeasureTime frame
Blood pressure (systolic pressure, diastolic pressure, mean pressure);

Secondary

MeasureTime frame
heart rate;blood lactate;PCO2;PH;

Countries

China

Contacts

Public ContactMingqing Peng

Yongchuan Hospital Of Chongqing Medical University, Chongqing, China

pengmingqing2016@163.com+86 18623104219

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026