Autism spectrum disorder
Conditions
Interventions
Intestinal microecological reconstruction:Fecal microbiota transplantation
Sponsors
Peking Union Medical College Hospital
Eligibility
Sex/Gender
All
Age
5 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1. Aged 5-12 years old, gender unlimited; 2. Diagnosed with autism spectrum disorder according to the evaluation of ADOS and ADI-R; 3. Stop use of antibiotics and other drugs that have an effect on intestinal microflora; 4. The parents or legal guardians of the children had good reading and comprehension skills and could complete the filling of the relevant assessment scale and follow-up; 5. The parents or legal guardians of the children sign the informed consent and volunteer to participate in the study.
Exclusion criteria
Exclusion criteria: 1. Coagulation dysfunction; 2. Intestinal obstruction, intestinal perforation, intestinal bleeding and other diseases that can cause severe systemic reactions by intestinal microecology reconstruction; 3. Other neurological, psychiatric or severe physical diseases except autism spectrum disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Autism Behavior Checklist (ABC); | — |
Secondary
| Measure | Time frame |
|---|---|
| Childhood Autism Rating Scale (CARS);Autism Diagnostic Observation Schedule (ADOS);Autism Diagnostic Interview-R (ADI- R);Autism Treatment Evaluation Checklist (ATEC); | — |
Countries
China
Contacts
Public ContactXin YOU
Peking Union Medical College Hospital
Outcome results
None listed