Skip to content

A randomized controlled trial of 25G plus pars plana vitrectomy for penetrating eye injury with high risk of proliferative-vetreoretionpathy in different timing

A randomized controlled trial of 25G plus pars plana vitrectomy for penetrating eye injury with high risk of proliferative-vetreoretionpathy in different timing

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800016191
Enrollment
Unknown
Registered
2018-05-17
Start date
2018-05-21
Completion date
Unknown
Last updated
2018-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ocular trauma

Interventions

Sponsors

Hebei Provincial Eye Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 18-70 years; 2. diagnosed as penetrating eye injury; 3. will undergo pars plana vitrectomy; 4. with high risk of PVR (meet at least one of the following): (1) zone 3 penetrating eye injury; (2) zone 1 or zone 2 penetrating eye injury with retinal laceration in zone 3; (3) massive vitreous hemorrhage; (4) retinal disorder (part of or whole retina cannot be recognized by B-ultrasonography.

Exclusion criteria

Exclusion criteria: 1. Patients who was injured for more than 4 days; 2. with a history of ocular trauma; 3. those in which endophthalmitis or intraocular foreign body was diagnosed at the initial presentation; 4. those who will undergo early endoscopic vitrectomy due to severe corneal edema and opacity; 5. those who will undergo postponed pars plana vitrectomy due to severe corneal edema and opacity; 6. with massive choroidal hemorrhage diagnosed by preoperative B-scan; 7. those who cannot tolerate pars plana vitrectomy due to other systematic diseases.

Design outcomes

Primary

MeasureTime frame
tPVR;retinal re-attachment;

Secondary

MeasureTime frame
BCVA;eye-globe saving;was zone 3 involved?;rupture of lens;vitreous hemorrhage;retinal detachment;choroidal injury;

Countries

China

Contacts

Public ContactLonghui Han

Hebei Provincial Eye Hospital

han-longhui@163.com+86 15631901373

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026