depression
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients meeting DSM-V diagnostic criteria of depressive disorder; 2. HAMD scores not less than 20 points; 3. Aged from 12-75 years; 5. The Han nationality, right handness; 6. Informed consent.
Exclusion criteria
Exclusion criteria: 1. With other psychotic symptoms; 2. With a history of alcohol and drug dependence; 3. With organic disease of brain and severe somatic disease; 4. With history of coma after brain trauma; 5. Woman with pregnancy or lactation period; 6. With a history of seizures or with a family history of epilepsy; 7. Received drugs in 6 hours before MRI scan; 8. Exclusion of other diseases; 9. With contraindications of MRI scan.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Brain structure;Brain function;HAMD;PHQ-9;HbA1c;SDS;SAS;MMSE;MoCA; | — |
Countries
China
Contacts
The First Affiliated Hospital of University of South China