neuroblastoma
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria for the screening/referral group: Infants younger than 1 year old: a. Cough for more than one month, Excluding Pulmonary Infection b. Myoclonus ocular clonus c. Intractable Diarrhea d. Masses or skin nodules found in the abdomen or chest Children aged 1-5 years have one or more of the following situations: a Fever and anemia of unknown origin b. Extensive lymphadenopathy c. Unexplained limb pain d. Pallor, fatigue, emaciation, irritability, sweating, loss of appetite e. Abdominal pain or diarrhea f. Dysfunction of limbs g. cular manifestations (unilateral exophthalmos, periorbital ecchymosis, nystagmus) h. Unexplained bruises Inclusion criteria for the control group: The control group comprised patients initially diagnosed with NB, who visited the oncology clinic directly in the corresponding period and were less than 5 years old.
Exclusion criteria
Exclusion criteria: 1. Parents disagree with screening; 2. Have congenital disease such as congenital hereditary metabolic disease ,congenital monstrosity, dysgnosia; 3. have history of malignant disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| age at diagnosis; | — |
Secondary
| Measure | Time frame |
|---|---|
| over all survival;event free survival; | — |
Countries
China
Contacts
Capital Medical University, Beijing Children's Hospital