Effect of esmolol on venous vascular tone in patients with septic shock

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1800016132

Enrollment

Unknown

Registered

2018-05-14

Start date

2018-06-01

Completion date

Unknown

Last updated

2018-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

septic shock

Interventions

esmolol group:esmolol infusion

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) severe infection and septic shock were consistent with the diagnostic criteria of the American Association of Chest Physicians / critical medical associations in 2012; (2) severe infection and septic shock were in accordance with the 2012 countries The guideline for interventilatory shock was given corresponding treatment; (3) mechanical ventilation with endotracheal intubation; and HR > 100 times /min.

Exclusion criteria

Exclusion criteria: (1) age < 18 years; (2) pregnancy; (3) Contraindication of arteria or internal jugular vein catheterization or rejection of pulse indication.Invasive cardiac output (PiCCO) monitoring and other invasive procedures.Failure, unstable angina pectoris, myocardial infarction, left ventricular ejection fraction <0.30. Bradycardia or heart block; central nervous system work. It can be combined with neurogenic shock, cerebrovascular accident and raumatic brain injury. The hemodynamics of vasoactive drugs is still fluctuating significantly.

Design outcomes

Primary

Measure	Time frame
venous vascular tone;	—

Countries

China

Contacts

Public ContactTao YU

Wannan Medical College First Affiliated Hospital, Yijishan Hospital

yutao197808@163.com+86 18855392038

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026