depression
Conditions
Interventions
Patients with major depressive disorder :NO
Sponsors
The First Affiliated Hospital of University of South China
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients with diatebes in accordance with the 2010 WHO criteria; 2. Patients meeting DSM-V diagnostic criteria of depressive disorder; 3. HAMD scores not less than 20 points; 4. Aged from 18-45 years; 5. The Han nationality, right handness; 6. Informed consent.
Exclusion criteria
Exclusion criteria: 1. With psychotic symptoms; 2. With a history of alcohol and drug dependence; 3. With organic disease of brain and severe somatic disease; 4. With history of coma after brain trauma; 5. Woman with pregnancy or lactation period; 6. With a history of seizures or with a family history of epilepsy; 7. Received drugs in 6 hours before MRI scan; 8. Exclusion of other diseases; 9. With contraindications of MRI scan.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Brain structure;Brain function;HAMD;PHQ-9;HbA1c;SDS;SAS;MMSE;MoCA; | — |
Countries
China
Contacts
Public ContactHong Zhou
The First Affiliated Hospital of University of South China
Outcome results
None listed