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Effect of radiofrequency ablation of genicular nerves at different temperatures in the treatment of knee osteoarthritis pain: A single center, randomized, double-blinded, controlled clinical trial

Effect of radiofrequency ablation of genicular nerves at different temperatures in the treatment of knee osteoarthritis pain: A single center, randomized, double-blinded, controlled clinical trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800016115
Enrollment
Unknown
Registered
2018-05-13
Start date
2018-05-01
Completion date
Unknown
Last updated
2018-05-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knee osteoarthritis

Interventions

Group A:the patient receieved ultrasound guided knee joint genicular nerve radiofrequency ablation treatment at 60 degrees Celsius
Group B:the patient receieved ultrasound guided knee joint genicular nerve radiofrequency ablation treatment at 70 degrees Celsius
Group C:the patient receieved ultrasound guided knee joint genicular nerve radiofrequency ablation treatment at 70 degrees Celsius

Sponsors

Nantong Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Diagnosed as knee osteoarthritis; 2. VAS score during walking = 3; 3. Kellgren–Lawrence grade II – IV; 4. Failed physical therapy drug therapyintraarticular injection therapy; 5. Signed the written informed consent.

Exclusion criteria

Exclusion criteria: 1. Coagulation disorder; 2. History of knee surgery; 3. Connective tissue diseases affecting the knee; 4. Received intraarticular injection treatment within the last three months; 5. Knee joint infection; 6. Mental disorder; 7. Impaired communication competence; 8. Cardiac pacemaker implanted; 9. Other reasons regarded unsuitable for enrollment.

Design outcomes

Primary

MeasureTime frame
Pain at Rest Assessed by Visual Analogue Scale;Pain at Rest Assessed by Visual Analogue Scale;Pain at Rest Assessed by Visual Analogue Scale;Pain at Rest Assessed by Visual Analogue Scale;Pain at Rest Assessed by Visual Analogue Scale;Pain during Walking Assessed by Visual Analogue Scale;Pain during Walking Assessed by Visual Analogue Scale;Pain during Walking Assessed by Visual Analogue Scale;Pain during Walking Assessed by Visual Analogue Scale;Pain during Walking Assessed by Visual Analogue Scale;

Secondary

MeasureTime frame
WOMAC score;WOMAC score;WOMAC score;WOMAC score;WOMAC score;

Countries

China

Contacts

Public ContactHongjie Yuan

Nantong Hospital of Traditional Chinese Medicine

yuanhongjie81@foxmail.com+86 13511570830

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026