Autism Spectrum Disorders
Conditions
Interventions
vitamin A deficiency:vitamin A supplementation
vitamin D deficiency:vitamin D supplementation
both vitamin A and vitamin D deficieny:vitamin A and vitamin D supplementation
Sponsors
Children's Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
1.5 Years to 18 Years
Inclusion criteria
Inclusion criteria: (1) Aged 1.5-18 years old, ASD patients identified by DSM-V, ADOS, SRS and ABC; (2) There were no positive signs of nervous system examination and no obvious psychomotor retardation; (3) No significant abnormalities were observed in EEG or MRI; (4) Vitamin A and vitamin D were not added within 2 months before entering the group.
Exclusion criteria
Exclusion criteria: History of other serious mental disorders, neurological diseases, chromosomal disease, inherited metabolic diseases, and other serious disease, such as audiovisual disorders, epilepsy, phenylketonuria, nodular brain sclerosis, neurofibroma, severe brain trauma, Autoimmune diseases, endocrine disease, cardiovascular, pulmonary disease, liver and kidney diseases. Guardians are reluctant to participate in researche.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| serum concentrations of vitamin A and vitamin D;Assessment of core symptoms of ASD; | — |
Secondary
| Measure | Time frame |
|---|---|
| sleeping problems;gastrointestinal tract problems;eating behavior;quality of life; | — |
Countries
China
Contacts
Public ContactDai Ying
Children's Hospital of Chongqing Medical University
Outcome results
None listed