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Applied Research on Evaluation of the Pregnancy Outcome and Developmental Potentiality of Oocyte by Bone Morphogenetic Protein 15 and Growth Differentiation Factor 9 in Patients with Poor Ovarian Response

Applied Research on Evaluation of the Pregnancy Outcome and Developmental Potentiality of Oocyte by Bone Morphogenetic Protein 15 and Growth Differentiation Factor 9 in Patients with Poor Ovarian Response

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800016107
Enrollment
Unknown
Registered
2018-05-11
Start date
2018-06-01
Completion date
Unknown
Last updated
2018-05-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infertility

Interventions

A (40 years):in vitro fertilization and embryo transfer

Sponsors

Sichuan Provincial Hospital For Woman and Children
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 45 Years

Inclusion criteria

Inclusion criteria: Patients with poor ovarian response who recieved IVF-ET in our reproductive center.Patients of tubal factors and normal ovarian response will be selected as control group.

Exclusion criteria

Exclusion criteria: 1. BMI=29 or <18.5; 2. Patients recieved controlled ovarian hyperstimulation in three months; 3. Patients with endometriosis,hyperprolactinemia,crine disease or metabolic disease; 4. Patients with the history of ovarian excision or raiotherapy; 5. Chromosomal abnormalities; 6. Patients whose husband's sperm is abnormal.

Design outcomes

Primary

MeasureTime frame
Clinical pregnancy rate;follicular fluid level of BMP-15;mRNA of BMP-15 in granular cell;—

Countries

China

Contacts

Public ContactYan Gong

Sichuan Provincial Hospital For Woman and Children

gongyan_496181657@qq.com+86 15208393996

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 24, 2026