Obesity
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 25 to 65 years male and female; 2. body mass index (BMI)=24 kg/m2; 3. light physical activity (i.e. < 3 h/week of light intensity exercise at 2.5 to 4.0 metabolic equivalents (METs) for 3 months prior to the study), weight stable for 3 months prior to the start of this study (i.e. less than 4 kg weight loss or weight gain in recent three months); 4. subjects are required to sign informed consent.
Exclusion criteria
Exclusion criteria: 1. women who are either in pre-menopause or 2 years post menopause; 2. Patients with diabetes (FPG = 7.0mmol/L and / or OGTT 2h PG = 11.1mmol/L); 3. attended in another study or take weight-loss drugs at the same time or 3 months prior to the beginning of the study; 4. the obvious renal insufficiency (creatinine=1.5 mg/dl or > 133umol/L); 5. the obvious abnormal liver function (ALT more than 2 times of the normal upper limit); 6. ever suffered from history of stroke or myocardial infarction; be done or are preparing to do coronary angioplasty or coronary artery bypass grafting; 7. other serious diseases such as malignant tumor; 8. be preparing for pregnancy; other situations that researchers believe that is not suitable for the selected object.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body Mass Index;Waist Circumference;Total Cholesterol;the relative abundance or composition of microorganisms in the gastrointestinal; | — |
Countries
China
Contacts
Nanchang Center for Disease Control and Prevention