Multicenter Randomized Open-label Clinical Trial Evaluating Acellular Dermal Matrix for Ocular Surface Reconstruction

Status

Recruiting

Phases

Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1800016050

Enrollment

Unknown

Registered

2018-05-08

Start date

2015-10-01

Completion date

Unknown

Last updated

2018-05-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

corneal

Interventions

Case series:marginal intrastromal lamellar keratoplasty

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) age 18–80 years without gender preference; (2) pellucid marginal corneal degeneration; (3) nidus corneal thickness less than 650nm; (4) willing to participated in the trial and sign the inform consent.

Exclusion criteria

Exclusion criteria: (1) contraindication for ocular surface surgery, such as active allergy, infection or inflammation; (2) extensive cornea thinning; (3) women during pregnancy or lactation

Design outcomes

Primary

Measure	Time frame
transparency;epithelium growth;neovascularization;keratocyte and nerve ingrowth;thickness;irregularity;	—

Secondary

Measure	Time frame
symptom;ocular sign;	—

Countries

China

Contacts

Public ContactXuemin Li

Peking University Third Hospital

13911254862@163.com+86 13911254862

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026