Diabetes related ocular surface disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Aged 50 to 75 years old, with or without diabetes, the level of HbA1c should lower than 7.8% in people with diabetes
Exclusion criteria
Exclusion criteria: People with proliferative diabetic retinopathy; People who had the history of corneal virus infection or had confirmed periphery neural diseases not related with DM; People who had undergone previous corneal or had ocular surgery or chronic use of topical ocular medications or use of ocular medication in recent 3 months; People who had severe systemic diseases influencing ocular or nerves.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SPEED score;Diabetic Retinopathy Assessment;tear film break up time;HbA1c;Schirmer I test;Fluorescein sodium staining;corneal sensitivity;tear meniscus height;corneal nerve length; | — |
Secondary
| Measure | Time frame |
|---|---|
| vision acuity;ocular pressure; | — |
Countries
China
Contacts
Tianjin Medical University Eye Hospital