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Randomized, controlled trial for subcutaneous injection of ozone in the treatment of postherpetic neuralgia

Randomized, controlled trial for subcutaneous injection of ozone in the treatment of postherpetic neuralgia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800016045
Enrollment
Unknown
Registered
2018-05-08
Start date
2019-01-01
Completion date
Unknown
Last updated
2018-05-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postherpetic neuralgia

Interventions

Group 2:low-level ozone treatment
Group 3:high-level ozone treatment

Sponsors

Second Hospital of Tianjin Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. meet the diagnostic criteria of postherpetic neuralgia patients: remain pain after healing three months in patient with herpes zoster to be treated, the affected nerve distribution area has severe spontaneous pain or seizure-like pain, and the nature is diverse, such as burning, Acupuncture, tight sensation, etc., accompanied with hyperalgesia or allodynia; 2. patient treated by standard drug course orally not resulted in effect or unable to tolerate adverse reactions; 3. Aged 18 years and more; 4. The average pain score more than 4 points in 24 hours.

Exclusion criteria

Exclusion criteria: severe heart, liver and kidney insufficiency 2 co-infection, history of cancer 3 mental system disorders or disturbance of consciousness can not be treated, oral expression is not clear 4 suffering from respiratory diseases, respiratory insufficiency.

Design outcomes

Secondary

MeasureTime frame
matrix metalloproteinase-1;Hypoxia inducible factor-1a;

Countries

China

Contacts

Public ContactKemei Shi

Second Hospital of Tianjin Medical University

kemeishi@126.com+86 13072081166

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026