Kidney and HBV
Conditions
Interventions
HBsAb titers 100 IU/L:Anti-Virals prophylaxis
Sponsors
Department of Urology/Institute of Urology/Organ Transplantation Center, West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
5 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. HBsAg(+) donor kidneys to HBsAg(-) recipients All recipients preoperative HBsAg(-), received HBsAg(+) donor kidneys, and donors had normal liver function before surgery [alanine aminotransferase (ALT) <50 U/L and total bilirubin (TB) )<28 umol/L]; 2. HBsAg(-)/HBcAb(+ donor kidneys to HBsAg(-)/HBcAb(-) recipients. All recipients preoperative HBsAg(-)/HBcAb(-) and received HBsAg(-)/HBcAb(+) donor kidneys, and the donor had normal liver function before KT. Such donors and recipients need to detect HBV-DNA before surgery and do not take preventive treatment.
Exclusion criteria
Exclusion criteria: 1. have received or are undergoing joint transplantation of organs other than the kidney; 2. recipients of double kidney transplantation; 3. HCV serum antibody positive for the recipient before surgery; 4. follow-up time of the recipient is less than 6 Months; 5. Post-transplant HBV serological status There are insufficient data available from the study report; 6. ABO blood group incompetent renal transplant recipients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HBV-DNA;HBV serum markers; | — |
Secondary
| Measure | Time frame |
|---|---|
| liver function post KT;renal gaft function; | — |
Countries
China
Contacts
Public ContactWang Xianding
Department of Urology/Institute of Urology/Organ Transplantation Center, West China Hospital, Sichuan University
Outcome results
None listed