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Efficacy of nalbuphine combined with propofol anesthesia in patients undergoing endoscopic retrograde cholangiopancreatography

Anesthetic effects of nalbuphine combined with propofol on patients receiving endoscopic mini-invasive therapy

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800016018
Enrollment
Unknown
Registered
2018-05-07
Start date
2018-05-01
Completion date
Unknown
Last updated
2018-05-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthetic management of ERCP procedure

Interventions

2:After intravenous injection of midazolam 1mg, intravenous nalbuterine 5mg will be injected intravenously and propofol 1-2mg/kg will be injected intravenously.
1:After intravenous injection of midazolam 1mg, fentanyl 50ug will be injected intravenously and propofol 1-2mg/kg will be injected intravenously.

Sponsors

Chinese PLA General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients receiving ERCP procedure; 2. Aged from 18 to 80 years old; 3. Body mass index ranged from 18.5 to 30 kg/m2; 4. ASA graded I-III.

Exclusion criteria

Exclusion criteria: 1. Patients with severe cardiovascular diseases, hepatic or renal insufficiency; 2. patients who have increased risk of alimentary tract obstruction, regurgitation and aspiration; 3. Patients who have contraindication of anticholinergic agents, such as glaucoma,pyloric obstruction and reflux esophagitis; 4. Patients fitted with a pacemaker; 5. A history of abnormal anesthesia recovery; 6. Hemoglobin less than 80g/L; 7. Abuse of opioids or sedative drugs; 8. Allergy to emulsion or opioids; 9. Patients who have mental disorders or are unable to communicate properly.

Design outcomes

Primary

MeasureTime frame
Hypoxemia;Upper airway obstruction;Apnea;Score of somatic movement;

Countries

China

Contacts

Public ContactMi Wei-dong

Anesthesia and Operation Center, Chinese PLA General Hospital

wwdd1962@aliyun.com+86 13381082966

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 13, 2026