Malignant and Non-malignant Biliary Stenoses
Conditions
Interventions
Gold Standard:Diagnosis of cancer was confirmed by pathological examination of tissue samples (PTCD,ERCP-brush, ERCP-biopsy, endoscopic ultrasonography–guided fine-needle aspiration or surgery) in all
Index test:Extracellular 
in 
and 
blood 
samples
Sponsors
Department of Interventional Oncology, Renji hospital,S chool of Medicine, Shanghai JiaoTong University
Eligibility
Sex/Gender
All
Age
16 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients scheduled for biliary interventional therapy due to obstructive jaundice or cholestasis of biliary origin (suspicion of cancer, suspicion of stones, chronic pancreatitis); 2. Aged > 16 years old; 3. Blood/Bile sample volume=3ml.
Exclusion criteria
Exclusion criteria: 1. Patients give up biliary interventional therapy due to obstructive jaundice or cholestasis of biliary origin (suspicion of cancer, suspicion of stones, chronic pancreatitis); 2. Blood/Bile sample volume<3ml; 3. Patients previously treated for obstructive jaundice.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Extracellular vesicles; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum CA19-9;Serum TBIL;Serum CRP;Bile total protein;Bile CEAM6;Serum DBIL; | — |
Countries
China
Contacts
Public ContactZhai Bo
Department of Interventional Oncology,Renji hospital,School of Medicine,Shanghai JiaoTong University
Outcome results
None listed