thoracic anesthesia
Conditions
Interventions
Gold Standard:oxygenation index, positive x ray chest film, pulmonary artery incarceration pressure or no increase of left atrial pressure, clinical presentations
Index test:End-tidal 
of 
(ETNO) 
continuously 
ventilation
Sponsors
The First Affiliated Hospital of Harbin Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Patient to scheduled to undergo lung resection, mediastinal tumour resection, or 3-incision oesophagectomy under general anaesthesia with double-lumen tube; 2) their one-lung ventilation time was expected to last more than 1 h; 3) ASA classification II or III.
Exclusion criteria
Exclusion criteria: 1) their body mass index (BMI) was greater than 35 kg/m2; 2) they smoked during the last 2 weeks; 3) they had asthma, chronic obstructive pulmonary disease (COPD) or other chronic lung disease and cannot suffer high mechanical stress during OLV; 4) vital capacity or forced expiratory volume in 1 s <50% of the predicted values in the lung function, 5) numbers of leukocytes less than 4.0 × 109/L or more than 10.0 × 109/L); 6) they had experienced acute lung injury or acute respiratory distress syndrome before surgery; 7) they had received mechanical ventilation within the last 30 days; 8) they were receiving systemic corticosteroid therapy, or intractable shock was considered; or 9) they failed to maintain oxygen saturation of pulse oximeter (SpO2) greater than 95% during two-lung ventilation and greater than 85% during OLV.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ETNO;SPE, SEN, ACC; | — |
Countries
China
Contacts
Public ContactEnyou Li
The First Affiliated Hospital of Harbin Medical University
Outcome results
None listed