subclinical chemotherapy-related cardiomyopathy in pediatric patients
Conditions
Interventions
Gold Standard:The American Society of Ultrasound and the European Cardiovascular Imaging Association defined cardiac dysfunction associated with cancer therapy in the form of a 10% reduction in left v
BNP,troponin
Sponsors
Chongqing Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. the experimental group is those children diagnosed by our hospital with primary lymphoma or leukemia and scheduled to undergo chemotherapy in our hospital; 2. The left ventricular ejection fraction (LVEF) was more than 55%; 3. The sinus arrhythmia was 60 < HR = 100 times/min); 4. the quality of two-dimensional echocardiography was good and the margin of left ventricular intima could be clearly displayed.
Exclusion criteria
Exclusion criteria: 1. Arrhythmia such as frequent ventricular premature, atrial fibrillation, atrioventricular block and so on; 2. Organic heart disease, such as coronary heart disease, cardiomyopathy, ventricular defect, etc.; 3. Systemic immune diseases, diabetes, uremia and hyperthyroidism lead to cardiac dysfunction; 4. Factors affecting image quality such as obesity or emphysema.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SR;Srl;EF; | — |
Countries
China
Contacts
Public ContactYang Chunjiang
Children's Hospital of Chongqing Medical University
Outcome results
None listed