antipsychotics
Conditions
Interventions
A1 Group (T-R):T-R in fast condition
A1 Group (R-T):R-T in fast condition
A2 Group (T-R):T-R in fed condition
A2 Group (R-T):R-T in fed condition
Sponsors
Beijing Shijitan Hospital Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. The subject is able to read and understand the Subject Information Sheet and Informed Consent Form; 2. The subject has signed the study-specific Informed Consent Form; 3. The subject is a man or woman can follow specific contraceptive measures . 4. The subject is >18 and 50 and 45 bpm; 7. The subject has a resting systolic blood pressure >91 and <140 mmHg and a resting diastolic blood pressure 51 and 90 mmHg at the Screening Visit and at the Baseline Visit; 8. The subject has a normal circadian rhythm; 9. The subject is, in the opinion of the investigator, generally healthy based on medical history, a physical examination, vital signs, an electrocardiogram (ECG), and the results of the clinical chemistry, haematology, urinalysis, serology, and other laboratory tests.
Exclusion criteria
Exclusion criteria: 1. The subject has taken disallowed medication 21 units per week for men or >14 units per week for women, or substance use (excluding nicotine or caffeine) deemed significant by the investigator, or a history of substance abuse (DSM-5? criteria) 5 years prior to the first dose of IMP; 9. The subject has had major surgery (excluding laparoscopic cholecystectomy or uncomplicated appendectomy) 5 times per day; 18. The subject has tested posi
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood Pressure;Pulse;Temperature;ECG;Blood Routine Examination;Routine Urine Examination;Blood Biochemical; | — |
Countries
China
Contacts
Public ContactXinghe Wang
Beijing Shijitan Hospital Capital Medical University
Outcome results
None listed