Hypertension
Conditions
Interventions
placebo group:oral placebo
experimental group 1:oral chokeberry extract
experimental group 2:oral tamato extract(fruitflow)
experimental group 3:oral cocoa extract
experimental group 4:oral casein-derived peptide formulas
Sponsors
Soochow University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-65 years old; 2. Grade I Hypertension SBP 140-159 or DBP 90-99 mmHg; 3. Have normal understanding and expression skills; 4. Informed consent.
Exclusion criteria
Exclusion criteria: 1. persons aged under 18 or above 65, pregnant or lactating women, allergic to the supplements; 2. Diabetes; 3. Obesity: BMI=28 kg/m2; 4. Target organ damage; 5. Diagnosis of cerebrovascular disease, heart disease, kidney disease, peripheral vascular disease, retinopathy; 6. Secondary hypertension patients; 7. Taking drugs that make blood pressure increased in recent 3 months: such as oral contraceptives, endosulfan, nasal drops, cocaine, amphetamine, steroids, non-steroidal anti-inflammatory drugs, erythropoietin, cyclosporine and licorice; 8. Patients are being treated with antibiotics, antibacterial, antiviral, chemotherapy, sterols, or immunotherapy; 9. Subjects who participate in research intervention in recent 30 days; Any other condition that may cause the subject to be at risk or may cause the subject to fail to understand or comply with the test requirements (the researchers determined). Withdraw criteria: 1. Subjects with poor compliance, taking less than the prescribed amount of 80% of the supplements or more than the required amount of 120%; 2. Suspension of research or failure to complete all examination items; 3. do not follow the research plan.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| blood pressure index; | — |
Secondary
| Measure | Time frame |
|---|---|
| lipids profile;glucose;inflammatory markers;Oxidative stress parameters;Endothelial function markers; | — |
Countries
China
Contacts
Public ContactLi-Hua Chen
Soochow University
Outcome results
None listed