Obstructive sleep apnea
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Male patients aged 30–65 years, admitted to PUMCH between May 2018 and April 2019 for diagnostic assessment of sleep disorders will be included.
Exclusion criteria
Exclusion criteria: 1. With central sleep apnea/hypopnea; 2. Suffered from diseases that affect bone metabolism, such as hypothyroidim, hyperthyroidism, malabsorption syndrome, primary hyperparathyroidism, hypoparathyroidismacromegaly, cushing syndrome, hypogonadism, chronic renal disease, malignancy or collagen disease; 3. Affected by diseases such as acute illness, cardiovascular disease, craniofacial abnormalities, lung disease, neurological or psychiatric disease; 4. Already receiving therapy of continuous positive airway pressure; 5. A history of immobilization within the previous 5 months or being wheelchair bound; 6. Taking anti-osteoporosis medication, glucocorticoid, calcium, vitamin D, parathormone, calcitonin, bisphosphonates, strontium ranelate, hypnotics, proton pump inhibitors, anticoagulant drugs, and anticonvulsant drugs, thiazides or chemotherapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ?????;pqct; | — |
Secondary
| Measure | Time frame |
|---|---|
| Metabolic indexes;Marker of inflammation and oxidative stress; | — |
Countries
China
Contacts
Chinese Academy of Medical Sciences, Peking Union Medical College Hospital