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Randomized controlled trial of Ginsenoside in treatment of knee osteoarthritis with bone marrow edema

Randomized controlled trial of Ginsenoside in treatment of knee osteoarthritis with bone marrow edema

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800015979
Enrollment
Unknown
Registered
2018-05-04
Start date
2018-01-01
Completion date
Unknown
Last updated
2018-05-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis combined with bone marrow edema

Interventions

experimental group:Ginsenoside

Sponsors

Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1) conforms to the diagnostic criteria of primary KOA; the kellgren & lawrence grade is II-III; Aged 40-70 years men and women; 2) the MRIT2 weighted images of the knee joint showed high signal intensity. Before treatment, there were complete imaging data, including lateral and lateral X-ray of the knee and MRI plain scan; 3) consent and signature of informed consent.

Exclusion criteria

Exclusion criteria: 1) secondary KOA; 2) combined with cerebrovascular, liver, kidney and mental diseases and other serious diseases; 3) suffering from joint tuberculosis, tumor, infectious arthritis, rheumatoid arthritis, ankylosing spondylitis, and A systemic disease, such as gout, psoriasis, etc.; 4) the history of trauma, fracture and operation of the knee; 5) fever is accompanied by a pain attack; 6) the course of the disease is non self limiting and progressively aggravated; 7) unable to cooperate with patients who completed case data collection and poor compliance.

Design outcomes

Primary

MeasureTime frame
WORMS;knee joint recovery;

Secondary

MeasureTime frame
WOMAC;

Countries

China

Contacts

Public ContactZheng Yuxin

Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine

sg_zyx1728@126.com+86 13816256086

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026