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Role of Circadian Rhythm for Cognitive Dysfunction in Post-operation patients

Role of Circadian Rhythm for Cognitive Dysfunction in Post-operation patients

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800015970
Enrollment
Unknown
Registered
2018-05-03
Start date
2018-05-07
Completion date
Unknown
Last updated
2018-05-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post Operation Cognitive Dysfunction

Interventions

Morning-operation group:no intervention
Afternoon-operation group:no intervention

Sponsors

Zhongshan Hospital of Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients are above 18-year old; 2. Patients have finished primary 9-year education in China; 3 Patients undergo general surgery; 4 Patients are not involved in other clinical trials.

Exclusion criteria

Exclusion criteria: 1. Patients have mental illness or cognitive dysfunction; 2. Patients are unable to complete Mini-Mental State Examination test due to their visual/auditory disease; 3. Patients are in advanced stage of cardiac, pulmonary, liver or renal disease; 4. Other conditions, including cannot understand Chinese language.

Design outcomes

Primary

MeasureTime frame
Mini-Mental State Examination;Delirium rating scale-R-98 scoresheet;—

Secondary

MeasureTime frame
postoperative complication;Bmal1 gene expression;IL-1, IL-6;S100ß, neuron-specific enolase (NSE);—

Countries

China

Contacts

Public ContactHao FANG

Zhongshan Hospital, Fudan University

drfanghao@163.com+86 13817826329

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026