repeated implantation failure
Conditions
Interventions
Treatment group:GnRH-a+hormone replacement therapy
Sponsors
Beijing Obstetrics and Gynecology Hospital,Capital Medical University
Eligibility
Sex/Gender
Female
Age
20 Years to 35 Years
Inclusion criteria
Inclusion criteria: 1. Women aged 20-35 years; 2. Regular menstrual cycles; 3. Normal ovarian reserve; 4. normal ovarian response; 5. Underwent two failed implantations; 6. The subjects must be volunteers and sign informed consents in person or by the legal representative.
Exclusion criteria
Exclusion criteria: 1. Polycystic ovarian syndrome; 2. B-mode ultrasound or hysteroscopy prompted intrauterine or endometrial lesion,including uterine malformation, endometriosis, adenomyosis, uterine tumor, endometrial polyp, endometrial hyperplasia, intrauterine adhesion,etc; 3. Hydrosalpinx; 4. medical comorbidities like diabetes mellitus, hyperthyreosis, heart disease and so on; 5. Use of drugs such as oral contraceptives, corticosteroides and other types of drugs that may affect the ovary function
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| implantation rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| clinical pregnancy rate;early abortion rate;live birth rate; | — |
Countries
China
Contacts
Public ContactYang Xiaokui
Beijing Obstetrics and Gynecology Hospital, Capital Medical University
Outcome results
None listed