Analgesia after laparoscopic pancreatoduodenectomy
Conditions
Interventions
experimental group:Thoracic Epidural Analgesia
control group:Intravenous Patient-controlled Analgesia
experimental group:ERAS protocol (Study Protocol)
control group:Conventional care (Study Protocol)
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Eligible patients were between 18 years and 75 years undergoing selective pancreaticoduodenectomy for ampullar periampullary or pancreatic head benign and malignant lesions; 2. Laparoscopic pancreaticoduodenectomy were successful performed; 3. The coagulation function is normal, platelet count 80-350 x 10^9/L 4. The renal function is normal.
Exclusion criteria
Exclusion criteria: 1. Laparoscopic pancreaticoduodenectomy convert open surgery,anticoagulation was needed when major vascular resection was performed intraoperatively; 2. The coagulation function is abnormal,epidural placement should be avoided during Low molecular weight heparin therapy or 24 hours after Low molecular weight heparin therapy; 3. Spine malformation,traumatic history of spine,psychiatric condition or communication (language) barriers should be precluded; 4. Patients with fever,evidence of infection,chronic pain,long-term narcotic use,history of anaphylaxis to local anesthetics or narcotics or surgery in the previous 30 days under general anesthesia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative pain score;Total opioid consumption; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time of intestinal function recovery;side effects of different analgesic methods;length of postoperative hospital stay;postoperative morbidity;Perioperative renal function; | — |
Countries
China
Contacts
Public ContactPeng Bing
West China Hospital, Sichuan University
Outcome results
None listed