nasopharyngeal carcinoma
Conditions
Interventions
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Case Group: 1. Nasopharyngeal carcinoma patients diagnosed by pathology, no distant metastasis observed, no dysphagia complained, Level 1 in water swallow test; 2. aged between 18 and 65 years old; 3. Capable of Basic self-care, no systemic swallowing function and voice function training received before; 4. Received radiotherapy or chemotherapy; 5. According to the purpose of research, enroll 100 living Nasopharyngeal carcinoma patients received treatment of different regimens and dosages. Control Group: 1. Collected from medical examination center of West China Hospital, basic characteristics matched with the experience group; 2. Normal structure of nose and throat, no defect and dysfunction of articulation system and articulation system; 3. Received no professional vocal or singing training before; 4. No smoking or larynx-related disease during the past 5 years.
Exclusion criteria
Exclusion criteria: Case Group 1. Nasopharyngeal carcinoma patients with distant metastasis or retreated 2. Received systemic swallowing function and voice function training before; 3. Having radiotherapy or larynx-related diseases before; 4. No capable of Basic self-care or with mental disorders. Control Group: 1. Not meet the criteria, aged over 65or below 18 years old; 2. With active respiratory diseases, nasal diseases(allergic rhinitis, chronic rhinitis or rhinosinusitis) or abnormal nasal structure; 3. With no olfactory function disorders; 4. With no mental retardation, mental disorder or depression; 5. During pregnancy or lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| M.D.Anderson Dysphagia Inventory, Chinese Version;water swallow test;Head-Neck Tumors Swallowing Ability Measurement, Chinese Version (HNSAM);EAT-1, Chinese Version;VHI-10??;SF-36;RTOG;VFSS;FEES;Acoustic analysis;Polysomnogram; | — |
Countries
China
Contacts
Public ContactDan Lu
West China Hospital of Sichuan University
Outcome results
None listed