Thyroid Nodules
Conditions
Interventions
A:single needle aspiration
B1:double needle aspiration: in the same plane of ultrasound
B2:double needle aspiration: at the two extremes of cystic nodules
Sponsors
Renji Hospital, School of Medicine, Shanghai Jiaotong University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) fine needle aspiration biopsy excluded the diagnosis of malignant tumor; (2) nodules are greater than 2cm or have nodular pain or influence aesthetics; (3) to exclude surgery or any minimally invasive treatment within 6 months; (4) aged 18-75 years; (5) in the process of fine needle aspiration biopsy, it has been proved that the substance in the capsule is more difficult to aspirate, such ascolloid and necrotic substance.
Exclusion criteria
Exclusion criteria: (1) the ultrasonography revealed the cystic malignant nodules and was confirmed by fine needle aspiration biopsy (FNAB); (2) history of cervical radiography; (4) family history of thyroid cancer; (5) history of hardener treatment; (6) serious heart, lung, kidney, immune system disease, coagulation function abnormality; (7) do not agree to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| preoperative nodule volume (V1);volume of solid components in preoperative nodules (V2);the volume of material in the inner capsule of the preoperative nodule (V3) =V1-V2.;postoperative nodular total volume (V4);the volume of solid components in postoperative nodules (V5);intrathecal volume of intrathecal sac (V6) = v4-v5.;the extraction rate after surgery (CJL%) = (V3-V6) /V3*100%.;the overall reduction rate of postoperative nodules (VRR%) = (V1-V4) /V1*100%.;complications occurred within 1 month after surgery.; | — |
Secondary
| Measure | Time frame |
|---|---|
| operation time (from the puncture needle into the nodule to all puncture needles to exit the skin);thyroid function before and after surgery.; | — |
Countries
China
Contacts
Public ContactXiaoyin Tang
Renji Hospital, School of Medicine, Shanghai Jiaotong University
Outcome results
None listed