congestive heart failure
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) aged above 18 years; 2) the extent of heart failure is assessed as stage III or IV based on the New York Heart Association (NYHA) functional classification; 3) heart function cannot be improved or sustained despite of maximal conservative treatment including large dose of diuretics; 4) recurrent hospitalization due to heart failure caused by volume overload (at least twice in the preceding 12 months).
Exclusion criteria
Exclusion criteria: 1) patients who suffered from an acute deterioration of heart and/or renal function; 2) estimated glomerular filtration rate (eGFR) calculated by Modification of Diet in Renal Disease (MDRD) equation is less than 10 mL/min/1.73m2; 3) ratio of serum urea to creatinine concentrations is less than or equal to 10.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| body weight;blood pressure;residual renal function;hemoglobin;albumin;urine output;peritoneal ultrafiltation;dialysis dosage;NYHA class;B-type natriuretic peptide;left ventricular ejection fractions; | — |
Countries
China
Contacts
Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School