pneumoconiosis
Conditions
Interventions
Control group:conventional treatment
Treatment group:conventional treatment and halotherapy(1 hour / day, 4 weeks)
pneumoconiosis phase I treatment group:conventional treatment and halotherapy(1 hour / day, 4 weeks)
pneumoconiosis phase I control group:conventional treatment
pneumoconiosis phase II treatment group:conventional treatment and halotherapy(1 hour / day, 4 weeks)
pneumoconiosis phase II control group:conventional treatment
pneumoconiosis phase III treatment group:conventional treatment and halotherapy(1 hour / day, 4 weeks)
pneumoconiosis phase III control group:conventional treatment
Pneumoconiosis combined with COPD treatment group:conventional treatment and halotherapy(1 hour / day, 4 weeks)
Pneumoconiosis combined with COPD control group:conventional treatment
Pneumoconiosis without COPD treatment group:conventional treatment and halotherapy(1 hour / day, 4 weeks)
Pneumoconiosis without COPD control group:conventional treatment
Sponsors
BEIDAIHE SANATORIUM OF CHINESE COAL MINERS (Institute of Occupational Disease Prevention and Treatment, Beidaihe, State Administration of Work Safety)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Aged 30-85 years old; (2) Patients were diagnosised by pneumoconiosis diagnostic criteria GBZ 70-2015; (3) According to GOLD 2015 copd diagnosis standard, the spirometric diagnosis of post-bronchodilator ratio of FEV1 to FVC of <70%, clinical features cough, sputum, dyspnea etc.; (4) Voluntary participation, signed informed consent.
Exclusion criteria
Exclusion criteria: (1) Patients combined with active pulmonary tuberculous or suffering from infectious diseases; (2) acute respiratory infections; (3) other server diseases affect cardiopulmonary function (including heart disease with decompensation of heart function).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cough symptoms score;expectoration symptoms score;COPD assessment test (CAT);quality of life score;MVV%pred(predicted value);FVC%pred(predicted value);FEV1/FVC;white blood cell count;red blood cell count;hemoglobin concentration;Eosinophil count;Monocyte count;platelet count;Serum ALT level;Serum AST level;Serum ALP level;C-reactive protein level;sputum interleukin-6 level, IL-6;sputum interleukin-8 level, IL-8;sputum tumour necrosis factor-a level, TNF-a;serum interleukin-4 level, IL-4;serum interleukin-8 level, IL-8;serum Interferon-?, IFN-?;serum Insulin-like Growth Factor-1, IGF-1;serum Insulin-like Growth Factor-2, IGF-2;serum Immunoglobulin E, IgE;serum Nitric oxide synthase, NOS; | — |
Countries
China
Contacts
Public ContactChen Gang
BEIDAIHE SANATORIUM OF CHINESE COAL MINERS (Institute of Occupational Disease Prevention and Treatment, Beidaihe, State Administration of Work Safety)
Outcome results
None listed