chemotherapy-induced nausea and vomiting
Conditions
Interventions
A:acupoint catgut embedding therapy
B:sham acupoint catgut embedding therapy
Sponsors
The First Affiliated Hospital of Guangzhou University of Chinese Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients were diagnosed as malignant tumors by pathology or cytology; 2. Patients would receive 3-day cisplatin-based (25mg/m2VDd1-3) combination chemotherapy during hospitalization; 3. Aged 18 to 70 years; 4. Eastern Cooperative Oncology Group performance status of 0–2; 5. Life expectancy of at least 3 months.(6)Participated in the study and signed informed consent.
Exclusion criteria
Exclusion criteria: cancer or metastasis in the brain; vomiting and retching within 24 h before chemotherapy; use of drugs with antiemetic activity, including benzodiazepines, within 48 h before chemotherapy; use of steroids within 72 h before chemotherapy; use of drugs (such as azole antifungal agents and clarithromycin) with possible effects on the metabolism of the study drugs within 1 week before chemotherapy; use of drugs (rifampin, phenytoin, carbamazepine and barbiturates) with possible effects on metabolism of the study drugs within 4 weeks before chemotherapy; abdominal radiotherapy within days 6 to 10 of chemotherapy; hypersensitivity to any component of the study regimen and receipt of stem cell transplantation in parallel with chemotherapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| complete response (CR; no vomiting/retching or rescue medication); | — |
Countries
China
Contacts
Public ContactYang Cao
The First Affiliated Hospital of Guangzhou University of Chinese Medicine
Outcome results
None listed