Dry eye disease
Conditions
Interventions
Acupuncture group:acupuncture
Sponsors
South Area of Guang'anmen Hospital, China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. individuals aged more than 18 years old and less than 60 years old; 2. participants meeting the diagnostic criteria of DED. The criteria of moderate to severe DED is based on the following ophthalmologic tests: a Schirmer I test (with the application of cocaine, a local anesthetic) value = 3 mm/5 minutes and = 9mm/5 minutes, a tear break-up time (TBUT) = 9 seconds and CFS = 1. These ophthalmologic tests will be performed by the ophthalmologists who don't know the results of random allocation; 3. Only the single eye with more severe scores or symptoms is selected to observe the outcome; and 4. participants who can complete the study, treatment, and assessments.
Exclusion criteria
Exclusion criteria: 1. participants who have undergone surgery for DED within 3 months; 2. participants with other ocular diseases (e.g., lacrimal duct obstruction, other conjunctiva and keratopathy) or immune system diseases (e.g., Sjogren syndrome and rheumatoid arthritis); 3. participantswith immune system diseases such as Sjogren syndrome and rheumatoid arthritis 4. participants with cardiovascular, liver, kidney, or hematopoietic system diseases, mental health disorders, or cancer for whom acupuncture may be inappropriate or unsafe; 5. participants who have received acupuncture within the past week; 6. women who are pregnant or lactating; 7. participants who are participating in other clinical trials; and 8. participants with a pacemaker, metal allergy, or severe fear of needles.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the Schirmer-I test; | — |
Countries
China
Contacts
Public ContactXue Zhang
South Area of Guang'anmen Hospital, China Academy of Chinese Medical Sciences
Outcome results
None listed