Recurrent Glioblastoma
Conditions
Interventions
TTF:temmozoldmide+tranilast+fasudil
Sponsors
Huashan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients of recurrent glioblastoma who once received surgery treatment and postoperative standard chemoradiation(TMZ program); 2. Patients between 18 and 70 yeaes old; 3. KPS scores=60; 4. WBC>4×10^9/L, Hb>90g/L; 5. Liver and kidney function are normal(CRE=150umol/LBUN=9mmol/LGOT GPT=2 times of upper limits); 6. Normal ECG; 7. No immune system disease, no history of hormone within 3 months before treatment, non-allergic to this cocktail-drugs; 8. Patients who are not included in other clinial trails; 9. Patiens or his/her authored agents who have approved to participant in this trial and signed the informed conscents.
Exclusion criteria
Exclusion criteria: 1. Patients who has the specific cause of cancer; 2. Pregnancy or breast-feeding women; 3. Patients who were included in other clinial trials during recent 3 months; 4. Patients with severe cardio-cerebral diseases; 5. Patients with low blood pressure; 6. Patients who were allergic to this cocktail-drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Survival time;Survival time;Patient condition;Monitoring of blood, cerebrospinal fluid;Neuroimaging examination; | — |
Countries
China
Contacts
Public ContactMao Ying
Huashan Hospital, Fudan University
Outcome results
None listed