FindTrial
Sign In

Determination of the 90% effective dose of intermittent intravenous phenylephrine for the treatment of spinal anesthesia-induced hypotension in severe pre-eclampsia parturients undergoing cesarean delivery: a sequential allocation dose-finding study

Determination of the 90% effective dose of intermittent intravenous phenylephrine for the treatment of spinal anesthesia-induced hypotension in severe pre-eclampsia parturients undergoing cesarean delivery: a sequential allocation dose-finding study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800015805
Enrollment
Unknown
Registered
2018-04-21
Start date
2018-04-23
Completion date
Unknown
Last updated
2018-04-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cesarean delivery

Interventions

Case series:phenylephrine

Sponsors

Womens' Hospital, School of Medicine, Zhejiang University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Patients with severe early onset preeclampsia (systolic blood pressure > 160 mmHg and/or diastolic blood pressure > 110 mmHg, on = 2 separate occasions; or symptoms of imminent eclampsia (headache, visual disturbance, epigastric pain) with = 3 + proteinuria

Exclusion criteria

Exclusion criteria: We do not recruit patients if they had a contra-indication to spinal anaesthesia; were in active labour; placenta previa or other placental abnormality; had a multiple pregnancy; pulmonary oedema; had a BMI > 40 kg.m2; umbilical cord prolapse; refuse to sign the informed consent

Design outcomes

Primary

MeasureTime frame
successful responses to phenylephrine;Fetal outcomes;—

Secondary

MeasureTime frame
The maternal outcomes;—

Countries

China

Contacts

Public ContactXiaowei Qian

Womens' Hospital, School of Medicine, Zhejiang University

qianxw@zju.edu.cn+86 15700157161

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026