Chronic obstructive pulmonary disease
Conditions
Interventions
Gold Standard:SBT(Spontaneous Breathing Test)
Index test:The 
Value 
of 
D-IWI 
to 
the 
extubation 
in 
COPD 
patients
Sponsors
The First Affiliated Hospital of Xi'an Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. clinical improvement of the underlying acute cause of respiratory failure; 2. Have the ability to breatheadequate cough reflex; 3. absence of excessive and/or purulent tracheobronchial secretion; 4. stable cardiovascular status (i.e., heart rate 92 % with inspiratory oxygen fraction (FiO2) =0.5 or arterial oxygen partial pressure to inspiratory oxygen fraction (PaO2/FiO2) =150 mmHg, both with positive endexpiratory pressure (PEEP) =8 cmH2O); 7. adequate pulmonary function (i.e., RR =30 breaths/min with VT=5 mL/kg ideal body weight (IBW) and no significant respiratory acidosis); 8. Richmond Agitation and Sedation Scale score ranging between –1 and +1.
Exclusion criteria
Exclusion criteria: 1. pregnant; 2. Presence of chest diseases such as pneumothorax, mediastinal pneumothorax or flail chest; 3. Rib fractures; 4. Neuromuscular diseases; 5. Use of muscle paralysis agents within 48 hours prior to study; 6. diaphragmatic ultrasound examination found that old or new one or both of the diaphragm paralysis or abnormal exercise.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bilateral diaphragm movement degree; | — |
Countries
China
Contacts
Public ContactWang Shengyu
Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Xi’an Medical University, Xi’an, Shaanxi, PR China
Outcome results
None listed