FindTrial
Sign In

Value of 131I-MIBG salivary gland imaging in the early diagnosis of Parkinson's disease

Value of 131I-MIBG salivary gland imaging in the early diagnosis of Parkinson's disease

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800015757
Enrollment
Unknown
Registered
2018-04-18
Start date
2019-04-01
Completion date
Unknown
Last updated
2018-04-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson's Disease

Interventions

Gold Standard:PD diagnostic criteria made by MDS in 2016
Index test:reduced&#32
uptake&#32
in&#32
salivery&#32
gland&#32
and&#32
myocardium&#32
I-131-MIBG&#32
scintigraphic&#32
imaging

Sponsors

Tongji hospital, Tongji University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. age 55-80 years old; 2. PD group.Patients of this group meet the 2016 PD diagnostic criteria made by MDS; 3. Cardiac disease group: (LVEF)<40%, severe arrythmia, Coronary stenosis of more than 50%, history of angina pectoris of myocardial infarction; 4. participants know the aim of this research and signed informed consents.

Exclusion criteria

Exclusion criteria: 1. patients with secondary Parkinson's disease or Parkinson plus syndrome; 2. patients with salivery diseases; 3. patients with severe pulmonary, liver, renal, immuno or hematological diseases; 4. patients with endocrine-metabolic diseases; 5. patients with PD and cardiac diseases; 6. patients with severe cognitive impairment or psychotic diseases or drug abuse.

Design outcomes

Primary

MeasureTime frame
salivery/forehead ratio;—

Secondary

MeasureTime frame
heart/upper mediastinum ratio;—

Countries

China

Contacts

Public ContactMa Hongxing

Tongji Hospital, Tongji University

mahongxing@tongji.edu.cn+86 15801709813

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026