morbid obesity
Conditions
Interventions
Obesity group I:given a single intravenous injection for propofol dosage of 2mg/kg according to total body weight(TBW)
Obesity group II:received a propofol dosage of 2mg/kg according to lean body weight(LBW).
normal group:given a single intravenous injection for propofol dosage of 2mg/kg according to total body weight(TBW)
Sponsors
Department of Anesthesiology,the First Affiliated Hospital,Jinan University ,Guangzhou
Eligibility
Sex/Gender
All
Age
15 Years to 50 Years
Inclusion criteria
Inclusion criteria: (1) between 20-45 years of age; (2) obesity index BMI = 35-40kg/m2,Normal weight patient body mass index 18.5-24kg/m2; (3) estimate the operation time between 2-2.5H; (4) according to the American Society of anesthesiologists standard ASA grade level I-II; (5) the function of lung, liver and kidney is normal, no other diseases such as cardiovascular system; (6) Patient is not allergic to propofol.
Exclusion criteria
Exclusion criteria: (1) with history of smoking; (2) Age less than 15 or greater than 50 according to the American Society of anesthesiologists standard ASA grade level III or above. Neurological dysfunction.Patients taking psychotropic drugs recently; (3) In addition to simple obesity, people with hypertension and/or diabetes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bispectral Index;Inflammatory mediator;Hemodynamic index;Blood concentration; | — |
Countries
China
Contacts
Public ContactXuemei Peng
the First Affiliated Hospital, Jinan University, Guangzhou
Outcome results
None listed